| 产品编号 | bs-13707R-AF594 |
| 英文名称 | Anti-PRELP/AF594 |
| 中文名称 | AF594标记的PRELP蛋白抗体 |
| 别 名 | 55 kDa leucine rich repeat protein of articular cartilage; MST161; MSTP161; Prelp; PRELP_HUMAN; Prolargin; Prolargin proteoglycan; Proline arginine rich end leucine rich repeat protein; Proline-arginine-rich end leucine-rich repeat protein; Proline/arginine rich end leucine rich repeat protein; SLRR2A. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 细胞外基质 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, ) |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PRELP |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: PRELP (proline/arginine-rich end leucine-rich repeat protein), also known as Prolargin, MST161, SLRR2A or MSTP161, is a 382 amino acid secreted protein that localizes to the extracellular matrix. Belonging to the Class II subfamily of the small leucine-rich proteoglycan (SLRP) family, PRELP contains twelve LRR (leucine-rich) repeats, which are motifs consisting of 20-29 residues that are present in numerous proteins with diverse functions and provide versatile structural framework for the formation of protein-protein interactions. Highly expressed in cartilage, basement membranes and developing bone, PRELP is considered a glycosaminoglycan (GAG)- and collagen-binding anchor protein that associates with the basement membrane heparan sulfate proteoglycan perlecan. PRELP acts as a linker between the extracellular matrix and the cell surface of proteoglycans and may be partially responsible for Hutchinson-Gilford progeria (HGP), an extremely rare genetic disorder that causes premature, rapid aging shortly after birth. Function: May anchor basement membranes to the underlying connective tissue. Subcellular Location: Secreted > extracellular space > extracellular matrix. Tissue Specificity: Connective tissue. Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. Contains 12 LRR (leucine-rich) repeats. Database links: Entrez Gene: 5549 Human Omim: 601914 Human SwissProt: P51888 Human Unigene: 632481 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
