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Rabbit Anti-NFS1/PE-Cy5.5 Conjugated antibody (bs-19227R-PE-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19227R-PE-Cy5.5
英文名称 Rabbit Anti-NFS1/PE-Cy5.5 Conjugated antibody
中文名称 PE-Cy5.5标记的半胱氨酸脱硫酶NFS1抗体
别    名 Cysteine desulfurase; Cysteine desulfurase, mitochondrial; HUSSY 08; IscS; mitochondrial; NFS1; NFS1 nitrogen fixation 1; NFS1 nitrogen fixation 1 homolog (S. cerevisiae); NFS1_HUMAN; NIFS; nitrogen fixation 1 (S. cerevisiae, homolog); nitrogen fixation gene 1; nitrogen-fixing bacteria S, homolog of; nitrogen-fixing bacteria S-like protein; OTTHUMP00000030799.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  信号转导  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NFS1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]

Function:
Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor.

Subcellular Location:
Cytoplasm. Nucleus and Mitochondrion.

Tissue Specificity:
Predominantly expressed in heart and skeletal muscle. Also found in brain, liver and pancreas.

Similarity:
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

Database links:

Entrez Gene: 9054 Human

Entrez Gene: 18041 Mouse

Entrez Gene: 84594 Rat

Omim: 603485 Human

SwissProt: Q9Y697 Human

SwissProt: Q9Z1J3 Mouse

SwissProt: Q99P39 Rat

Unigene: 194692 Human

Unigene: 283604 Mouse

Unigene: 3151 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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