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Rabbit Anti-ADRB3/beta 3 Adrenergic Receptor/PE Conjugated antibody (bs-10921R-PE)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10921R-PE
英文名称 Anti-ADRB3/beta 3 Adrenergic Receptor/PE
中文名称 PE标记的β3肾上腺素能受体抗体
别    名 beta 3 Adrenergic Receptor; beta3-adrenergic receptor; beta3-AR; adrenergic; beta-3- receptor; ADR B3; ADRB 3; ADRB3; ADRB3R; Adrenergic beta 3 receptor; B3AR; Beta 3 adrenoceptor; Beta 3 adrenoreceptor; Beta 3AR; B3AR; BETA3AR; ADRB3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  神经生物学  生长因子和激素  细胞膜受体  内分泌病  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat,  (predicted: Horse, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human beta 3 Adrenergic Receptor
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
beta 3 Adrenergic Receptor is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Beta adrenergic receptors are involved in the epenephrine and norepinephrine-induced activation of adenylate cyclase through the action of G proteins. beta 3 Adrenergic Receptor expression has been documented in adipose tissues, heart, and in smooth muscle of digestive and urinary tract organs (bladder, colon, small intestine, stomach, ureter). Utilization of alternate promoters and/or 3-prime untranslated regions may result in tissue-specific regulation of the expression of this protein.

Function:
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed mainly in adipose tissues.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.

Database links:

Entrez Gene: 155 Human

Entrez Gene: 11556 Mouse

Entrez Gene: 25645 Rat

SwissProt: P13945 Human

SwissProt: P25962 Mouse

SwissProt: P26255 Rat

Unigene: 2549 Human

Unigene: 278475 Mouse

Unigene: 10100 Rat

Omim: 109691 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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