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Rabbit Anti-NMD3/PE-Cy3 Conjugated antibody (bs-19288R-PE-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19288R-PE-Cy3
英文名称 Rabbit Anti-NMD3/PE-Cy3 Conjugated antibody
中文名称 PE-Cy3标记的NMD3蛋白抗体
别    名 60S ribosomal export protein NMD3; CGI 07; FLJ21053; hNMD3; NMD3 homolog; NMD3 homolog (S. cerevisiae).  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  神经生物学  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NMD3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Ribosomes are composed of 60S and 40S subunits that are assembled in the nucleolus and exported to the cytoplasm through nuclear pore complexes in the nuclear envelope. NMD3 is an adaptor for 60S subunit export via the CRM1 (XPO1; MIM 602559) pathway (Trotta et al., 2003 [PubMed 12773398]).[supplied by OMIM, Mar 2008]

Function:
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.

Subunit:
Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.

Subcellular Location:
Cytoplasm. Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.

Similarity:
Belongs to the NMD3 family.

Database links:

Entrez Gene: 51068 Human

Entrez Gene: 509871 Cow

Entrez Gene: 488137 Dog

Entrez Gene: 97112 Mouse

Entrez Gene: 310512 Rat

Omim: 611021 Human

SwissProt: Q96D46 Human

SwissProt: Q99L48 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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