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Rabbit Anti-DMRTA2/APC Conjugated antibody (bs-14348R-APC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-14348R-APC
英文名称 Anti-DMRTA2/APC
中文名称 APC标记的DMRTA2蛋白抗体
别    名 DMRT A2; DMRT like family A2; DMRT5; DMRTA 2; dmrta2; DMTA2_HUMAN; Doublesex- and mab-3-related transcription factor 5; Doublesex- and mab-3-related transcription factor A2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  干细胞  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DMRTA2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
DMRTA2 is a 542 amino acid protein that localizes to the nucleus and contains one DM DNA-binding domain. Expressed testis, DMRTA2 is thought to be involved in sexual developmental processes during maturation. The gene encoding DMRTA2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Function:
May be involved in sexual development.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in testis.

Similarity:
Belongs to the DMRT family.
Contains 1 DM DNA-binding domain.

Database links:

Entrez Gene: 63950 Human

Entrez Gene: 242620 Mouse

Entrez Gene: 313471 Rat

SwissProt: Q5TFQ3 Human

SwissProt: Q96SC8 Human

SwissProt: A2A9A2 Mouse

Unigene: 334481 Human

Unigene: 32825 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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