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Rabbit Anti-GTF3C6/BF350 Conjugated antibody (bs-16362R-BF350)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16362R-BF350
英文名称 Rabbit Anti-GTF3C6/BF350 Conjugated antibody
中文名称 BF350标记的通用转录因子3C多肽6/TFIIIC35抗体
别    名 bA397G5.3; C6ORF51; General transcription factor 3C polypeptide 6; General transcription factor IIIC polypeptide 6 alpha; GTF3C6; TF3C6_HUMAN; TFIIIC 35 kDa subunit; TFIIIC35; Transcription factor IIIC 35 kDa subunit; Transcription factor IIIC 35kDa; Transcription factor IIIC polypeptide 6; Transcription factor IIIC subunit 6.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 免疫学  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GTF3C6
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.[supplied by OMIM, Mar 2008]

Function:
Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the TFIIIC subunit 6 family.

Database links:

Entrez Gene: 112495 Human

Omim: 611784 Human

SwissProt: Q969F1 Human

Unigene: 418520 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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