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Rabbit Anti-KLHDC10/PE-Cy3 Conjugated antibody (bs-16757R-PE-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16757R-PE-Cy3
英文名称 Anti-KLHDC10/PE-Cy3
中文名称 PE-Cy3标记的KLHDC10蛋白抗体
别    名 Kelch domain containing 10; Kelch domain-containing protein 10; KIAA0265; KLD10_HUMAN; Klhdc10; OTTHUMP00000212347; PNAS 119; Scruin like at the midline homolog; Slim.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Human, Mouse, Cow, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KLHDC10
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
KLHDC10 is a 442 amino acid protein that contains six kelch repeats. Expressed in fetal brain, liver, lung, kidney and placenta, KLHDC10 exists as two alternatively spliced isoforms. The gene encoding KLHDC10 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia.

Subunit:
Interacts with CUL2, TCEB1 and TCEB2; may be the substrate recognition component of an E3 ubiquitin ligase complex.

Subcellular Location:
Nucleus

Similarity:
Contains 6 Kelch repeats.

Database links:

Entrez Gene: 23008 Human

Entrez Gene: 76788 Mouse

SwissProt: Q6PID8 Human

SwissProt: Q6PAR0 Mouse

Unigene: 520710 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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