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Rabbit Anti-Kv1.2/PE-Cy5.5 Conjugated antibody (bs-16865R-PE-Cy5.5) ~~~促销,代码KX240301~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16865R-PE-Cy5.5
英文名称 Anti-Kv1.2/PE-Cy5.5
中文名称 PE-Cy5.5标记的电压门控钾通道Kv1.2抗体
别    名 Akr6a4; BK2; HBK5; HK4; HUKIV; Kca1 2; kcna2; KV1.2; MGC50217; Mk 2; MK2; NGK1; Potassium voltage gated channel shaker related subfamily member 2; Potassium voltage-gated channel subfamily A member 2; RBK2; Voltage gated potassium channel subunit Kv1.2. KCNA2_HUMAN   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  神经生物学  通道蛋白  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Kv1.2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Kv1.2 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which K(+) ions may pass in accordance with their electrochemical gradient. Kv1.2 binds PDZ domains of DLG1, DLG2 and DLG4. The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.

Function:
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

Subunit:
Heterotetramer of potassium channel proteins.

Subcellular Location:
Membrane; Multi-pass membrane protein

Similarity:
Belongs to the potassium channel family.

Database links:

Entrez Gene: 395117 Chicken

Entrez Gene: 3737 Human

Entrez Gene: 16490 Mouse

Entrez Gene: 25468 Rat

Omim: 176262 Human

SwissProt: P16389 Human

SwissProt: P63141 Mouse

SwissProt: P63142 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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