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Rabbit Anti-KCNS1/Gold Conjugated antibody (bs-16916R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-16916R-Gold
英文名称 Rabbit Anti-KCNS1/Gold Conjugated antibody
中文名称 胶体金标记的电压门控钾通道亚基KV9.1抗体
别    名 Delayed rectifier K(+) channel alpha subunit 1; Delayed-rectifier K(+) channel alpha subunit 1; K+ voltage gated channel, subfamily S, 1; KCNS1; KCNS1_HUMAN; KV9.1; OTTHUMP00000031783; potassium voltage gated channel delayed rectifier protein; potassium voltage gated channel delayed rectifier protein S1; potassium voltage gated channel, delayed rectifier, subfamily S, member 1; Potassium voltage-gated channel subfamily S member 1; voltage gated potassium channel protein Kv9.1; Voltage gated potassium channel subunit Kv9.1; Voltage-gated potassium channel subunit Kv9.1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  神经生物学  信号转导  通道蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Human, Mouse, Dog, Cow, Horse, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNS1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. [provided by RefSeq, Jul 2008]

Function:
Potassium channel subunit. Modulates channel activity and reduces the ion flow.

Subcellular Location:
Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.

Tissue Specificity:
Detected in all tissues tested with the exception of skeletal muscle. Highly expressed in adult and fetal brain, fetal kidney and lung, and adult prostate and testis.

Similarity:
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily.

Database links:

Entrez Gene: 3787 Human

Omim: 602905 Human

SwissProt: Q96KK3 Human

Unigene: 117780 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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