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Rabbit Anti-GTF2H3/BF488 Conjugated antibody (bs-16352R-BF488)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16352R-BF488
英文名称 Rabbit Anti-GTF2H3/BF488 Conjugated antibody
中文名称 BF488标记的通用转录因子2H亚基3/TTFIIH p34抗体
别    名 Basic transcription factor 2 34 kDa subunit; BTF2; BTF2 p34; General transcription factor IIH polypeptide 3; General transcription factor IIH subunit 3; general transcription factor IIH, polypeptide 3, 34kDa; Gtf2h3; P34; TF2H3_HUMAN; TFB4; TFIIH; TFIIH basal transcription factor complex p34 subunit; Transcription factor IIH 34 kDa subunit.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Chinese Hamster)
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GTF2H3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012]

Function:
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Anchors XPB.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the TFB4 family.

Database links:

Entrez Gene: 2967 Human

Entrez Gene: 511896 Cow

Entrez Gene: 100059174 Horse

Entrez Gene: 209357 Mouse

Entrez Gene: 288651 Rat

Omim: 601750 Human

SwissProt: Q05B56 Cow

SwissProt: Q13889 Human

SwissProt: Q8VD76 Mouse

SwissProt: Q561R7 Rat

Unigene: 355348 Human

Unigene: 185467 Mouse

Unigene: 203542 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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