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Rabbit Anti-LARP1/AF555 Conjugated antibody (bs-17101R-AF555)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-17101R-AF555
英文名称 Anti-LARP1/AF555
中文名称 AF555标记的LARP1蛋白抗体
别    名 1810024J12Rik; 3110040D16Rik; KIAA0731; La related protein; La ribonucleoprotein domain family, member 1; LARP; MGC19556; mKIAA0731; rCG_32791; RGD1306683; RP23-293I3.7.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  细胞凋亡  结合蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LARP1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
LARP1 is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3. Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing.

Function:
LARP1 belongs to the LARP family and contains 1 HTH La-type RNA-binding domain.

Subunit:
Interacts with PABPC1/PABP. Associates with the mTORC1 complex. Interacts with EIF4E.

Subcellular Location:
Cytoplasm

Similarity:
Belongs to the LARP family.
Contains 1 HTH La-type RNA-binding domain.

Database links:

Entrez Gene: 23367 Human

Omim: 612059 Human

SwissProt: Q6PKG0 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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