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Rabbit Anti-TRMT5/PE-Cy5 Conjugated antibody (bs-17145R-PE-Cy5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-17145R-PE-Cy5
英文名称 Rabbit Anti-TRMT5/PE-Cy5 Conjugated antibody
中文名称 PE-Cy5标记的TRMT5蛋白抗体
别    名 KIAA1393; M1G methyltransferase; M1G-methyltransferase; TRM5; TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae); TRMT5; TRMT5_HUMAN; tRNA (guanine-N(1)-)-methyltransferase; tRNA [GM37] methyltransferase; tRNA methyltransferase 5; tRNA N1G37 methyltransferase.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRMT5
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM, Mar 2008]

Function:
Specifically methylates guanosine-37 in various tRNAs. Not dependent on the nature of the nucleoside 5' of the target nucleoside.

Subunit:
Monomer.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the TRM5 / TYW2 family.

Database links:

Entrez Gene: 57570 Human

Entrez Gene: 76357 Mouse

Omim: 611023 Human

SwissProt: Q32P41 Human

SwissProt: Q9D0C4 Mouse

Unigene: 380159 Human

Unigene: 311344 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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