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Rabbit Anti-HMG4/HMGB3/Gold Conjugated antibody (bs-8809R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-8809R-Gold
英文名称 Rabbit Anti-HMG4/HMGB3/Gold Conjugated antibody
中文名称 胶体金标记的高迁移率家族蛋白3抗体
别    名 High mobility group (nonhistone chromosomal) protein 4; High mobility group box 3; High mobility group protein 2a; High mobility group protein 4; High mobility group protein B3; High mobility group protein HMG4; HMG 4; HMG-2a; HMG-4; HMG2A; HMGB 3; HMGB3; HMGB3_HUMAN; MGC90319; Non histone chromosomal protein; Nonhistone chromosomal protein HMG4.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  信号转导  转录调节因子  结合蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HMG4/HMGB3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM, Mar 2008]

Function:
Binds preferentially single-stranded DNA and unwinds double stranded DNA.

Subcellular Location:
Nucleus. Chromosome.

Tissue Specificity:
Expressed predominantly in placenta.

Similarity:
Belongs to the HMGB family.
Contains 2 HMG box DNA-binding domains.

Database links:

Entrez Gene: 3149 Human

Entrez Gene: 613729 Cow

Entrez Gene: 15354 Mouse

Entrez Gene: 305373 Rat

Omim: 300193 Human

SwissProt: Q32L31 Cow

SwissProt: O15347 Human

SwissProt: O54879 Mouse

Unigene: 19114 Human

Unigene: 336087 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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