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Rabbit Anti-SHOX2/APC Conjugated antibody (bs-17471R-APC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-17471R-APC
英文名称 Rabbit Anti-SHOX2/APC Conjugated antibody
中文名称 APC标记的身材矮小同源盒基因SHOX2抗体
别    名 Homeobox protein Og12X; OG 12; OG 12X; OG12; OG12X; OGI 2X; OGI2X; Paired related homeobox protein SHOT; Paired-related homeobox protein SHOT; Short stature homeobox 2; Short stature homeobox homolog; Short stature homeobox protein 2; SHOT; SHOX 2; SHOX homologous gene on chromosome 3; SHOX2; SHOX2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  信号转导  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SHOX2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

Function:
May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in heart, skeletal muscle, liver, lung, bone marrow fibroblast, pancreas and placenta.

Similarity:
Belongs to the paired homeobox family. Bicoid subfamily.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 6474 Human

Entrez Gene: 20429 Mouse

Entrez Gene: 25546 Rat

Omim: 602504 Human

SwissProt: O60902 Human

SwissProt: P70390 Mouse

SwissProt: O35750 Rat

Unigene: 55967 Human

Unigene: 39093 Mouse

Unigene: 11258 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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