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Rabbit Anti-mu Crystallin/HRP Conjugated antibody (bs-17900R-HRP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-17900R-HRP
英文名称 Anti-mu Crystallin/HRP
中文名称 辣根过氧化物酶标记的CRYM蛋白抗体
别    名 CRYM; CRYM_HUMAN; Crystallin mu; DFNA 40; DFNA40; Ketimine reductase; Mu crystallin homolog; Mu-crystallin homolog; NADP regulated thyroid hormone binding protein; NADP-regulated thyroid-hormone-binding protein; OTTHUMP00000115878; THBP; Thiomorpholine carboxylate dehydrogenase.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  生长因子和激素  结合蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Sheep, Cat, )
产品应用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human mu Crystallin
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]

Function:
Binds thyroid hormone. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in neural tissue, muscle and kidney.

Similarity:
Belongs to the ornithine cyclodeaminase family.

Database links:

Entrez Gene: 1428 Human

Entrez Gene: 505167 Cow

Entrez Gene: 12971 Mouse

Entrez Gene: 117024 Rat

Omim: 123740 Human

SwissProt: Q14894 Human

SwissProt: O54983 Mouse

SwissProt: Q9QYU4 Rat

Unigene: 924 Human

Unigene: 9114 Mouse

Unigene: 24561 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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