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Rabbit Anti-SPATA9/AP Conjugated antibody (bs-17635R-AP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-17635R-AP
英文名称 Rabbit Anti-SPATA9/AP Conjugated antibody
中文名称 碱性磷酸酶(AP)标记的精子发生相关蛋白9抗体
别    名 FLJ35906; NYD SP16; spermatogenesis associated 9; Spermatogenesis associated protein 9; Testis development protein NYD SP16.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  发育生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,  (predicted: Human, Pig, Cow, Sheep, )
产品应用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPATA9
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
SPATA9 is a 254 amino acid single-pass membrane protein that is highly expressed in testis and pancreas with low expression in heart, lung, and brain. A component of the sperm acrosome, SPATA9 may participate in sperm capacitation and acrosome reaction, and is therefore necessary for fertilization. SPATA9 is also suggested to be involved in testicular development/spermatogenesis and may be an important factor in male infertility. No expression of SPATA9 was found in patients affected by Sertoli-cell-only syndrome, also known as Del Castillo syndrome or germ cell aplasia, which is characterized by male sterility without sexual abnormality. SPATA9 is encoded by a gene located on human chromosome 5, which consists of about 181 million base pairs, encodes around 1,000 genes and represents about 6% of human genomic DNA.

Function:
SPATA9 may play a role in testicular development/spermatogenesis and may be an important factor in male infertility. Three named isoforms exist.

Subcellular Location:
Membrane; Single-pass membrane protein

Database links:

Entrez Gene: 83890 Human

Omim: 608039 Human

SwissProt: Q9BWV2 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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