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Rabbit Anti-B3GALNT1/AF647 Conjugated antibody (bs-10438R-AF647)
~~~促销,代码KT240603~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10438R-AF647
英文名称1 Rabbit Anti-B3GALNT1/AF647 Conjugated antibody
中文名称 AF647标记的β1,3半乳糖转移酶3抗体
别    名 3-galactosyltransferase 3; 3-GalNAc-T1; 3-GalTase 3; 3-N-acetylgalactosaminyltransferase 1; 3-N-acetylgalactosaminyltransferase; b3Gal T3; b3Gal-T3; B3galnt1; B3GALT3; B3GL1_HUMAN; Beta 1,3 galactosyltransferase 3; Beta 1,3 GalTase 3; beta 1,3 N acetylgalactosaminyltransferase 1 (globoside blood group); Beta 3 GalNAc T1; Beta 3 Gx T3; Beta-1; Beta-3-Gx-T3; beta3Gal T3; Beta3Gal-T3; Beta3GalT3; brainiac1; Galactosylgalactosylglucosylceramide beta D acetyl galactosaminyltransferase; Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; galT3; Gb4Cer; GLCT3; GLOB; Globoside synthase; globotriaosylceramide 3 beta N acetylgalactosaminyltransferase; P antibody P antigen synthase; P blood group globoside; P1 antibody UDP Gal:betaGlcNAc beta 1,3 galactosyltransferase 1; UDP Gal:betaGlcNAc beta 1,3 galactosyltransferase, polypeptide 3 (Globoside blood group); UDP GalNAc:beta 1,3 N acetylgalactosaminyltransferase 1; UDP GalNAc:betaGlcNAc beta 1,3 galactosaminyltransferase, polypeptide 1 (Globoside blood group); UDP N acetylgalactosamine:globotriaosylceramide beta 1,3 N acetylgalactosaminyltransferase; UDP-GalNAc:beta-1; UDP-N-acetylgalactosamine:globotriaosylceramide beta-1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human B3GALNT1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein.

Function:
Transfers N-acetylgalactosamine onto globotriaosylceramide.

Subcellular Location:
Golgi apparatus membrane; Single-pass type II membrane protein.

Tissue Specificity:
Higher expression in heart and brain, and to a lesser extent in lung, placenta, kidney and testis. Lower expression in liver, spleen and stomach.

Similarity:
Belongs to the glycosyltransferase 31 family.

Database links:

Entrez Gene: 8706 Human

Entrez Gene: 26879 Mouse

Entrez Gene: 310508 Rat

Omim: 603094 Human

SwissProt: O75752 Human

SwissProt: Q920V1 Mouse

SwissProt: Q6AY39 Rat

Unigene: 418062 Human

Unigene: 153710 Mouse

Unigene: 3666 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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