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Rabbit Anti-MBIP/MAP3K12 binding inhibitory protein 1/RBITC Conjugated antibody (bs-18662R-RBITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-18662R-RBITC
英文名称 Anti-MBIP/MAP3K12 binding inhibitory protein 1/RBITC
中文名称 罗丹明(RBITC)标记的MAP3K12结合抑制蛋白1抗体
别    名 MAP3K12 binding inhibitory protein 1; MAP3K12-binding inhibitory protein 1; MAPK upstream kinase binding inhibitory protein; MAPK upstream kinase-binding inhibitory protein; MBIP; MBIP1_HUMAN; MUK binding inhibitory protein; MUK-binding inhibitory protein; OTTHUMP00000178844.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MBIP/MAP3K12 binding inhibitory protein 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 Function:
Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.

Subunit:
Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5.

Subcellular Location:
Nucleus. Cytoplasm. Shows a cytoplasmic localization when coexpressed with MAP3K12.

Tissue Specificity:
Ubiquitous. High expression seen in the heart and lung.

Database links:

Entrez Gene: 51562 Human

Entrez Gene: 217588 Mouse

Entrez Gene: 362740 Rat

Omim: 609431 Human

SwissProt: Q9NS73 Human

SwissProt: Q99LQ1 Mouse

Unigene: 368647 Human

Unigene: 25656 Mouse

Unigene: 24202 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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