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Rabbit Anti-NAT1/AF488 Conjugated antibody (bs-19027R-AF488)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19027R-AF488
英文名称 Anti-NAT1/AF488
中文名称 AF488标记的芳酰胺乙酰化酶1抗体
别    名 AAC1; ARY1_HUMAN; Arylamide acetylase 1; Arylamine N acetyltransferase 1; Arylamine N-acetyltransferase 1; MNAT; Monomorphic arylamine N acetyltransferase; Monomorphic arylamine N-acetyltransferase; N acetyltransferase type 1; N-acetyltransferase type 1; NAT 1; NAT-1; nat1; NATI.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAT1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Function:
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the arylamine N-acetyltransferase family.

Database links:

Entrez Gene: 9 Human

Entrez Gene: 17960 Mouse

Entrez Gene: 116631 Rat

Omim: 108345 Human

SwissProt: P18440 Human

SwissProt: P50294 Mouse

SwissProt: P50297 Rat

Unigene: 2 Human

Unigene: 591847 Human

Unigene: 14125 Mouse

Unigene: 37420 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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