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Rabbit Anti-MGAT4C/AF555 Conjugated antibody (bs-18909R-AF555)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-18909R-AF555
英文名称1 Rabbit Anti-MGAT4C/AF555 Conjugated antibody
中文名称 AF555标记的MGAT4C蛋白抗体
别    名 3-D-mannoside beta-1; 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; 4-N-acetylglucosaminyltransferase IVc; Alpha-1; GlcNAc-T IVc; GnT-IVc; hGnT-IV-H; MGAT4C; MGT4C_HUMAN; N-acetylglucosaminyltransferase IV homolog; N-acetylglucosaminyltransferase IVc; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine: alpha-1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MGAT4C
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
MGAT4C is a 478 amino acid single-pass type II membrane protein that localizes to the golgi apparatus and belongs to the glycosyltransferase 54 family. Expressed in liver, heart, testis, brain and adrenal gland, GnT-IVH functions as a glycosyltransferase that catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans, thereby playing a crucial role in the production of tri- and tetra-antennary N-linked sugar chains. The gene encoding GnT-IVH maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.

Function:
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity).

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas.

Similarity:
Belongs to the glycosyltransferase 54 family.

Database links:

Entrez Gene: 25834 Human

SwissProt: Q9UBM8 Human

Unigene: 589093 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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