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Rabbit Anti-PRRG1/AF350 Conjugated antibody (bs-19433R-AF350)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19433R-AF350
英文名称 Anti-PRRG1/AF350
中文名称 AF350标记的跨膜γ羧基酸蛋白1抗体
别    名 PRGP1; Proline rich gamma carboxyglutamic acid protein 1; Proline rich Gla (G carboxyglutamic acid) 1; Proline rich Gla (G carboxyglutamic acid) polypeptide 1; Proline rich Gla protein 1; Proline-rich gamma-carboxyglutamic acid protein 1; Proline-rich Gla protein 1; PRRG1; TMG1; TMG1_HUMAN; Transmembrane gamma carboxyglutamic acid protein 1 [Precursor]; Transmembrane gamma-carboxyglutamic acid protein 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Cow, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRRG1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]

Subcellular Location:
Membrane.

Tissue Specificity:
Highly expressed in the spinal cord.

Post-translational modifications:
Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent gamma-carboxylase.

Similarity:
Contains 1 Gla (gamma-carboxy-glutamate) domain.

Database links:

Entrez Gene: 785916 Cow

Entrez Gene: 5638 Human

Entrez Gene: 546336 Mouse

Entrez Gene: 363472 Rat

Omim: 604428 Human

SwissProt: A7Z070 Cow

SwissProt: O14668 Human

Unigene: 190341 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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