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Rabbit Anti-PRRX2/Gold Conjugated antibody (bs-19434R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-19434R-Gold
英文名称 Anti-PRRX2/Gold
中文名称 胶体金标记的中胚层配对同源蛋白2抗体
别    名 Paired mesoderm homeobox protein 2; Paired related homeobox protein 2; paired-like homeobox gene 2; paired-like homeodomain protein PRX2; Paired-related homeobox protein 2; PMX2; Predicted NUP98/PRRX2 fusion protein; Prrx2; PRRX2_HUMAN; PRX 2; PRX-2; PRX2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  免疫学  发育生物学  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRRX2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008]

Function:
May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development.

Subcellular Location:
Nucleus.

Tissue Specificity:
In fetal skin, highest expression found in cells of mesodermal origin within the dermal papilla of the developing hair shaft. Not detected in epidermis or dermis. In adult skin, weakly expressed within the basal layers of the epidermis. Not expressed in dermis.

Similarity:
Belongs to the paired homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 51450 Human

Entrez Gene: 20204 Mouse

Entrez Gene: 113931 Rat

Omim: 604675 Human

SwissProt: Q99811 Human

SwissProt: Q06348 Mouse

Unigene: 660115 Human

Unigene: 1802 Mouse

Unigene: 93004 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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