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Rabbit Anti-UGT1A7/Biotin Conjugated antibody (bs-20068R-Bio)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-20068R-Bio
英文名称 Anti-UGT1A7/Biotin
中文名称 生物素标记的尿苷二磷酸葡糖醛基转移酶1A7抗体
别    名 GNT1; UGT1A7; OTTHUMP00000065199; UD17_HUMAN; UDP glucuronosyltransferase 1A7; UDP glucuronosyltransferase; UDP glycosyltransferase 1 family polypeptide A7; UDP-glucuronosyltransferase 1 family polypeptide A7s; UDP-glucuronosyltransferase 1-7; UDP-glucuronosyltransferase 1-G; UDP-glucuronosyltransferase 1A7; UDPGT; UDPGT 1-7; UGT-1G; UGT1; UGT1*7; UGT1-07; UGT1.7; UGT1A7; UGT1G.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,  (predicted: Pig, )
产品应用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from rat UGT1A7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols. [provided by RefSeq, Jul 2008]

Function:
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.

Subcellular Location:
Microsome. Endoplasmic reticulum membrane.

Tissue Specificity:
Liver and gastric tissue.

Similarity:
Belongs to the UDP-glycosyltransferase family.

Database links:

Entrez Gene: 54577 Human

Omim: 606432 Human

SwissProt: Q9HAW7 Human

Unigene: 554822 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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