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Rabbit Anti-phospho-FOXO6 (Ser184)/BF350 Conjugated antibody (bs-20061R-BF350)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-20061R-BF350
英文名称 Rabbit Anti-phospho-FOXO6 (Ser184)/BF350 Conjugated antibody
中文名称 BF350标记的磷酸化叉头蛋白O6抗体
别    名 Foxo6 (phospho Ser184); Foxo6 (phospho S184); Forkhead box protein O6; FOXO6_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human FOXO6 around the phosphorylation site of Ser184
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Murine Foxo6 is a member of the murine forkhead family of transcription factors. This family consists of over 30 members, the vast majority of which is important in embryonic development. These forkhead transcription factors may play a role in maintenance and survival of developing and adult neurons.

Function:
Transcriptional activator.

Subcellular Location:
Cytoplasmic and Nuclear. When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors.

Post-translational modifications:
Phosphorylation of Ser-184 is be important in regulating the transacriptional activity.

Similarity:
Contains 1 fork-head DNA-binding domain.

Database links:

Entrez Gene: 100132074 Human

Entrez Gene: 329934 Mouse

Entrez Gene: 313558 Rat

Omim: 611457 Human

SwissProt: A8MYZ6 Human

SwissProt: Q70KY4 Mouse

Unigene: 277090 Mouse

Unigene: 190858 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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