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Rabbit Anti-RTN4RL1/PE-Cy3 Conjugated antibody (bs-20071R-PE-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-20071R-PE-Cy3
英文名称 Anti-RTN4RL1/PE-Cy3
中文名称 PE-Cy3标记的Nogo66受体相关蛋白3抗体
别    名 DKFZp547J144; NgR 3; NgR3; NGRH 2; NGRH2; NGRL2; Nogo 66 receptor homolog 2; Nogo 66 receptor related protein 3; Nogo receptor like 2; Reticulon 4 receptor like 1; R4RL1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RTN4RL1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
NgR3 is a 441 amino acid protein that belongs to the Nogo receptor family. Localized to the cell membrane, NgR3 contains 8 LRR (leucine-rich) repeats. NgR3 is predominantly expressed in brain, where it localizes to the surface of neurons, but is also found at lower levels in lung, placenta, kidney, mammary gland, skeletal muscle, spleen and salivary gland. NgR3 is thought to play a role in the regulation of axonal regeneration and plasticity in the adult central nervous system. The gene that encodes NgR3 maps to human chromosome 17, which makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes.

Function:
RTN4RL1 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor. Note: Localized to the surface of neurons, including axons

Tissue Specificity:
Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen.

Similarity:
Belongs to the Nogo receptor family.
Contains 8 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

Database links:

Entrez Gene: 146760 Human

Entrez Gene: 237847 Mouse

Entrez Gene: 303311 Rat

Omim: 610461 Human

SwissProt: Q86UN2 Human

SwissProt: Q8K0S5 Mouse

SwissProt: Q80WD0 Rat

Unigene: Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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