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Rabbit Anti-NUDT10/HRP Conjugated antibody (bs-19508R-HRP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19508R-HRP
英文名称 Anti-NUDT10/HRP
中文名称 辣根过氧化物酶标记的NUDT10蛋白抗体
别    名 NUD10_HUMAN; Diphosphoinositol polyphosphate phosphohydrolase 3-alpha; DIPP-3-alpha; DIPP3-alpha; hDIPP3alpha; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha; AltName: Diadenosine hexaphosphate hydrolase (AMP-forming); AltName: Nucleoside diphosphate-linked moiety X motif 10; Nudix motif 10; hAps2.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, )
产品应用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NUDT10
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
NUDT10 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates (Hidaka et al., 2002 [PubMed 12105228]).[supplied by OMIM, Mar 2008]

Function:
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is widely expressed.

Similarity:
Belongs to the Nudix hydrolase family. DIPP subfamily.
Contains 1 nudix hydrolase domain.

Database links:

Entrez Gene: 170685 Human

Entrez Gene: 616931 Cow

Entrez Gene: 102954 Mouse

Entrez Gene: 58242 Mouse

Entrez Gene: 367747 Rat

Omim: 300527 Human

SwissProt: Q58CW0 Cow

SwissProt: Q8NFP7 Human

SwissProt: P0C027 Mouse

Unigene: 375178 Human

Unigene: 41198 Mouse

Unigene: 426101 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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