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Rabbit Anti-PARVA/HRP Conjugated antibody (bs-19892R-HRP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19892R-HRP
英文名称 Anti-PARVA/HRP
中文名称 辣根过氧化物酶标记的基质重塑相关蛋白PARVA抗体
别    名 Actopaxin; Alpha parvin; Alpha-parvin; Calponin like integrin linked kinase binding protein; Calponin-like integrin-linked kinase-binding protein; CH ILKBP; CH-ILKBP; FLJ10793; FLJ12254; Matrix remodelling associated 2; Matrix remodelling associated protein 2; Matrix-remodeling-associated protein 2; MXRA 2; MXRA2; PARV A; PARVA; PARVA_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Cow, )
产品应用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PARVA
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]

Function:
Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. Plays a role in ciliogenesis.

Subcellular Location:
Cell junction > focal adhesion. Cell membrane. Cytoplasm > cytoskeleton. Constituent of focal adhesions.

Tissue Specificity:
Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver.

Similarity:
Belongs to the parvin family.
Contains 2 CH (calponin-homology) domains.

Database links:

Entrez Gene: 55742 Human

Entrez Gene: 57342 Mouse

Entrez Gene: 57341 Rat

Omim: 608120 Human

SwissProt: Q9NVD7 Human

SwissProt: Q9EPC1 Mouse

SwissProt: Q9HB97 Rat

Unigene: 432914 Human

Unigene: 143763 Mouse

Unigene: 92564 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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