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Rabbit Anti-PARP9/APC Conjugated antibody (bs-19890R-APC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19890R-APC
英文名称 Anti-PARP9/APC
中文名称 APC标记的多腺苷二磷酸多聚酶PARP9抗体
别    名 ADP-ribosyltransferase diphtheria toxin-like 9; ARTD9; AW214463; B aggressive lymphoma protein; Bagl; BAL; BAL1; BC003281; DKFZp666B0810; DKFZp686M15238; EC 2.4.2.30; FLJ26637; FLJ35310; FLJ41418; FLJ43593; MGC:7868; MGC156739; MGC7868; OTTMUSP00000028034; PARP 9; PARP-9; Parp9; PARP9_HUMAN; Poly (ADP ribose) polymerase family member 9; Poly [ADP-ribose] polymerase 9; RGD1307534.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  b-淋巴细胞  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 97kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PARP9
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 Function:
Involved in inducing the expression of IFN-gamma-responsive genes.

Subcellular Location:
Cytoplasm > cytosol. Nucleus. Shuttles between the nucleus and the cytosol. Export to the cytosol depends on the interaction with DTX3L.

Tissue Specificity:
Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form. Most abundantly expressed in lymphomas with a brisk host inflammatory response. In diffuse large B-cell lymphomas tumors, expressed specifically by malignant B-cells.

DISEASE:
Note=Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration. May therefore be involved in promoting B-cell migration and dissemination of high-risk DLB-CL tumors.

Similarity:
Contains 2 Macro domains.
Contains 1 PARP catalytic domain.

Database links:

Entrez Gene: 83666 Human

Entrez Gene: 80285 Mouse

SwissProt: Q8IXQ6 Human

SwissProt: Q8CAS9 Mouse

Unigene: 518200 Human

Unigene: 49074 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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