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Rabbit Anti-PYGO1/Gold Conjugated antibody (bs-19692R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-19692R-Gold
英文名称 Anti-PYGO1/Gold
中文名称 胶体金标记的PYGO1蛋白抗体
别    名 PYGO 1; PYGO1; PYGO1_HUMAN; Pygopus homolog 1 (Drosophila); Pygopus homolog 1; Pygopus like protein 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  发育生物学  干细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PYGO1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 Function:
Involved in signal transduction through the Wnt pathway.

Subunit:
Interacts with BCL9 via The PHD-type zinc finger motiv, and thereby becomes part of the nuclear beta-catenin/TCF complex. Identified in a complex with BCL9L, CDC73, CTNNB1 and PYGO1.Interacts with histone H3 mono-, di- or tri-methylated at 'Lys4' (H3K4me1, H3K4me2, H3K4me3); the interaction is enhanced by the interaction with BCL9.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 PHD-type zinc finger.

Database links:

Entrez Gene: 26108 Human

Entrez Gene: 72135 Mouse

Entrez Gene: 691857 Rat

Omim: 606902 Human

SwissProt: Q9Y3Y4 Human

SwissProt: Q9D0P5 Mouse

Unigene: 256587 Human

Unigene: 273605 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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