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Rabbit Anti-SLC5A11/Gold Conjugated antibody (bs-21020R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-21020R-Gold
英文名称 Anti-SLC5A11/Gold
中文名称 胶体金标记的碳酸氢钠协同转运蛋白4-A11抗体
别    名 homolog of rabbit KST1; KST1; Na(+)/myo-inositol cotransporter 2; na+/myo-inositol cotransporter 2; putative sodium-coupled cotransporter RKST1; RKST1; SC5AB_HUMAN; SGLT6; SLC5A11; SMIT2; sodium-dependent glucose cotransporter; sodium/glucose cotransporter KST1; sodium/myo-inositol cotransporter 2; Sodium/myo-inositol transporter 2; solute carrier family 5 (sodium/glucose cotransporter), member 11; solute carrier family 5 member 11.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC5A11
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].[supplied by OMIM, Mar 2008]

Function:
Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.

Subcellular Location:
Membrane.

Tissue Specificity:
Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes.

Similarity:
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Database links:

Entrez Gene: 115584 Human

Omim: 610238 Human

SwissProt: Q8WWX8 Human

Unigene: 164118 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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