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Rabbit Anti-SLC22A7/PE-Cy5 Conjugated antibody (bs-19808R-PE-Cy5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19808R-PE-Cy5
英文名称 Rabbit Anti-SLC22A7/PE-Cy5 Conjugated antibody
中文名称 PE-Cy5标记的溶质载体家族蛋白22成员A7抗体
别    名 hOAT2; liver specific transporter; NLT; Novel liver transporter; OAT2; Organic anion transporter 2; Organic anion transporter member 7; Organic anion transporter member 7 Fragment; S22A7_HUMAN; SLC22A7; solute carrier family 22 (organic anion transporter) member 7; Solute carrier family 22; Solute carrier family 22 member 7.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  信号转导  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC22A7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate.

Subcellular Location:
Basolateral cell membrane. Apical side of the renal tubule.

Tissue Specificity:
Expressed in liver and kidney.

Similarity:
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

Database links:

Entrez Gene: 10864 Human

Entrez Gene: 108114 Mouse

Entrez Gene: 733693 Pig

Entrez Gene: 89776 Rat

Omim: 604995 Human

SwissProt: Q9Y694 Human

SwissProt: Q91WU2 Mouse

SwissProt: Q1RPP5 Pig

SwissProt: Q5RLM2 Rat

SwissProt: Q63314 Rat

Unigene: 485438 Human

Unigene: 387538 Mouse

Unigene: 10009 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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