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Rabbit Anti-Plexin D1/Biotin Conjugated antibody (bs-12739R-Bio)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12739R-Bio
英文名称 Anti-Plexin D1/Biotin
中文名称 生物素标记的神经丛蛋白D1抗体
别    名 KIAA0620; MGC75353; PLEX D1; PLEXD 1; PLEXD1; Plexin-D1; PlexinD1; PLXD1_HUMAN; PLXN D1; PLXND 1; PLXND1; PLXND1 protein.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
产品应用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 208kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Plexin D1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 Function:
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature (By similarity). Mediates anti-angiogenic signaling in response to SEMA3E.

Subunit:
Interacts with NRP1, SEMA4A, SEMA3A, SEMA3C and SEMA3E.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Detected at low levels in heart, placenta, lung, skeletal muscle, kidney, thymus and liver. Detected at very low levels in brain, colon, spleen, small intestine and peripheral blood leukocytes.

Similarity:
Belongs to the plexin family.
Contains 3 IPT/TIG domains.
Contains 1 Sema domain.

Database links:

Entrez Gene: 23129 Human

Entrez Gene: 67784 Mouse

Omim: 604282 Human

SwissProt: Q9Y4D7 Human

SwissProt: Q3UH93 Mouse

SwissProt: Q68HV1 Mouse

SwissProt: Q8VCL8 Mouse

SwissProt: Q9CZF2 Mouse

Unigene: 301685 Human

Unigene: 3085 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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