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Rabbit Anti-Surb7/RBITC Conjugated antibody (bs-12845R-RBITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12845R-RBITC
英文名称 Anti-Surb7/RBITC
中文名称 罗丹明(RBITC)标记的Surb7蛋白抗体
别    名 MED21; hSrb7; MED21; MED21_HUMAN; Mediator complex subunit 21; Mediator of RNA polymerase II transcription subunit 21; RNA polymerase II holoenzyme component SRB7; RNAPII complex component SRB7; SRB7; SRB7 suppressor of RNA polymerase B homolog; Surb7.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 15kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Surb7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Mediator complex subunit 21 family.

Database links:

Entrez Gene: 418216 Chicken

Entrez Gene: 539496 Cow

Entrez Gene: 9412 Human

Entrez Gene: 108098 Mouse

Entrez Gene: 312849 Rat

Entrez Gene: 406732 Zebrafish

Omim: 603800 Human

SwissProt: Q2TBU8 Cow

SwissProt: Q13503 Human

SwissProt: Q9CQ39 Mouse

SwissProt: Q7ZTI5 Zebrafish

Unigene: 286145 Human

Unigene: 26212 Mouse

Unigene: 81879 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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