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Rabbit Anti-TBC1D10A/FITC Conjugated antibody (bs-4464R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-4464R-FITC
英文名称 Anti-TBC1D10A/FITC
中文名称 FITC标记的TBC结构域TB10A蛋白抗体
别    名 dJ130H16.1; dJ130H16.2; EBP50 PDZ interactor of 64 kD; EBP50-PDX interactor of 64 kDa; EPI 64; EPI64; EPI64 protein; Rab27A-GAP-alpha; TB10A_HUMAN; TBC1 domain family member 10A; TBC1D10; TBC1D10A.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TBC1D10A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
TBC1D10A (TBC1 Domain Family Member 10A) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and TBC/RABGAPs. GO annotations related to this gene include GTPase activator activity and PDZ domain binding. An important paralog of this gene is TBC1D10B.

Function:
Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A.

Subcellular Location:
Cell projection > microvillus. Localizes to the microvilli-rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells.

Post-translational modifications:
Exists in both phosphorylated and non-phosphorylated state.

Similarity:
Contains 1 Rab-GAP TBC domain.

Database links:

Entrez Gene: 83874 Human

Entrez Gene: 103724 Mouse

Entrez Gene: 360968 Rat

Omim: 610020 Human

SwissProt: Q9BXI6 Human

SwissProt: P58802 Mouse

Unigene: 655273 Human

Unigene: 28140 Mouse

Unigene: 105859 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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