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Rabbit Anti-PFDN3/APC Conjugated antibody (bs-12628R-APC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12628R-APC
英文名称 Rabbit Anti-PFDN3/APC Conjugated antibody
中文名称 APC标记的希佩尔-林道结合蛋白抗体
别    名 HIBBJ 46; HIBBJ46; PFD 3; PFD3; PFD3_HUMAN; PFDN 3; Prefoldin 3; Prefoldin subunit 3; Prefoldin3; VBP 1; VBP-1; VBP1; VHL binding protein 1; VHL-binding protein 1; Von Hippel Lindau binding protein 1; Von Hippel-Lindau-binding protein 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  转录调节因子  结合蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, 
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PFDN3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015]

Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Subcellular Location:
Cytoplasm. Nucleus. In complex with VHL can translocate to the nucleus.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the prefoldin subunit alpha family.

Database links:

Entrez Gene: 508727 Cow

Entrez Gene: 481089 Dog

Entrez Gene: 7411 Human

Entrez Gene: 22327 Mouse

Omim: 300133 Human

SwissProt: Q2TBX2 Cow

SwissProt: P61758 Human

SwissProt: P61759 Mouse

Unigene: 436803 Human

Unigene: 8294 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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