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Rabbit Anti-PKD1L2/FITC Conjugated antibody (bs-12691R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12691R-FITC
英文名称 Rabbit Anti-PKD1L2/FITC Conjugated antibody
中文名称 FITC标记的多囊肾蛋白1样蛋白2抗体
别    名 PC1 like 2 protein; PC1-like 2 protein; PK1L2_HUMAN; PKD1L 2; Pkd1l2; Polycystic kidney disease 1 like protein 2; Polycystic kidney disease 1-like protein 2; Polycystic kidney disease protein 1-like 2; Polycystin 1 like 2; Polycystin-1L2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 271kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PKD1L2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. This gene appears to be a polymorphic pseudogene in humans, where some individuals contain a non-functional allele. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Function:
May function as an ion-channel regulator. May function as a G-protein-coupled receptor.

Subunit:
May interact via its C-terminus with GNAS and GNAI1.

Tissue Specificity:
Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney.

Similarity:
Belongs to the polycystin family.
Contains 1 C-type lectin domain.
Contains 1 GPS domain.
Contains 1 PLAT domain.

Database links:

Entrez Gene: 114780 Human

Omim: 607894 Human

SwissProt: Q7Z442 Human

Unigene: 413525 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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