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Rabbit Anti-RANBP17/PE Conjugated antibody (bs-21153R-PE)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-21153R-PE
英文名称 Anti-RANBP17/PE
中文名称 PE标记的RAN结合蛋白17抗体
别    名 Exp 7; Exp7; Exportin 7; Exportin7; KIAA0745; RAN binding protein 16; RANBP 16; XPO 7; XPO7.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  结合蛋白  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Chimpanzee, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RANBP17
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]

Function:
May function as a nuclear transport receptor.

Subcellular Location:
Cytoplasm. Nucleus. Nucleus > nuclear pore complex.

Tissue Specificity:
Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.

Similarity:
Belongs to the exportin family.

Database links:

Entrez Gene: 739299 Chimpanzee

Entrez Gene: 529222 Cow

Entrez Gene: 479293 Dog

Entrez Gene: 64901 Human

Entrez Gene: 100526145 Pig

Entrez Gene: 303029 Rat

Omim: 606141 Human

SwissProt: Q9H2T7 Human

Unigene: 410810 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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