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Rabbit Anti-Myoglobin/PE-Cy5 Conjugated antibody (bs-41107R-PE-Cy5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-41107R-PE-Cy5
英文名称 Anti-Myoglobin/PE-Cy5
中文名称 PE-Cy5标记的肌红蛋白抗体
别    名 MYO; MB; MGC13548; PVALB; MYG_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 Purified Human Myoglobin (Natural Human Myoglobin protein)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.

Function:
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Similarity:
Belongs to the globin family.

Database links:

Entrez Gene: 4151 Human

Entrez Gene: 17189 Mouse

Entrez Gene: 59108 Rat

Omim: 160000 Human

SwissProt: P02144 Human

SwissProt: P04247 Mouse

SwissProt: Q9QZ76 Rat

Unigene: 517586 Human

Unigene: 404074 Mouse

Unigene: 40511 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

肌红蛋白存在于肌肉中,心肌中含量特别丰富,,有较高的组织特异性,是横纹肌的特异性标记物,但对肿瘤的敏感性较差。主要用于横纹肌肿瘤的诊断与鉴别诊断。少数恶性中胚叶混合瘤、睾丸畸胎瘤、肾母细胞瘤亦可见阳性表达。
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