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Rabbit Anti-RBM42/FITC Conjugated antibody (bs-21296R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-21296R-FITC
英文名称 Rabbit Anti-RBM42/FITC Conjugated antibody
中文名称 FITC标记的RNA结合蛋白42抗体
别    名 MGC10433; RNA binding motif protein 42; RNA binding protein 42.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 结合蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RBM42
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
RNA binding motif protein 42 (RBM42) C-terminal domain interacts with HNRNPK C-terminla domain and RNA. RBM42 and HNRNPK are involved in the maintenance of cellular ATP levels during stress, possibly by protecting critical mRNAs. Upon stress response, RBM42 localizes with HNRNPK in cytoplasmic aggregates of stalled translational pre-initiation complexes called stress granules. There are 4 isoforms produced by alternative splicing.

Function:
Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA.

Subunit:
Interacts with HNRNPK.

Subcellular Location:
Cytoplasmic and Nuclear.

Similarity:
Belongs to the RRM RBM42 family.
Contains 1 RRM (RNA recognition motif) domain.

Database links:

Entrez Gene: 79171 Human

Entrez Gene: 68035 Mouse

Entrez Gene: 361545 Rat

GenBank: NP_077297.2 Human

Omim: 613232 Human

SwissProt: Q9BTD8 Human

SwissProt: Q91V81 Mouse

SwissProt: Q6AXT7 Rat

Unigene: 5086 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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