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Rabbit Anti-P2Y1/HRP Conjugated antibody (bs-23150R-HRP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-23150R-HRP
英文名称 Rabbit Anti-P2Y1/HRP Conjugated antibody
中文名称 辣根过氧化物酶标记的P2Y1受体抗体/嘌呤受体抗体
别    名 ATP receptor; P2 purinoceptor subtype Y1; P2RY1; P2Y purinoceptor 1; P2Y1 purinoceptor; Platelet ADP receptor; Purinergic receptor; Purinergic receptor P2Y G protein coupled 1; Purinergic receptor P2Y1; P2RY1_HUMAN; P2Y1 purinoceptor.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 信号转导  转录调节因子  通道蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human P2Y1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Constituents: 0.01M PBS, pH 7.4 with 10 mg/mL BSA and 0.1% Gentamicin, 50% glycerol. Or Lyophilized. Buffer = 0.01M PBS, pH 7.4 with 10 mg/mL BSA and 0.1% Gentamicin. Reconstitute with sterile distilled water.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]

Function:
Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in muscle, heart, liver, kidney, lung, brain, spleen, but not in testis.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 100135592 Guinea pig

Entrez Gene: 5028 Human

Entrez Gene: 18441 Mouse

Entrez Gene: 25265 Rat

Omim: 601167 Human

SwissProt: P59902 Guinea pig

SwissProt: P47900 Human

SwissProt: P49650 Mouse

SwissProt: P49651 Rat

Unigene: 654526 Human

Unigene: 281452 Mouse

Unigene: 10217 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

P2Y1 receptor 为离子通道蛋白,一种受体配体开启的离子通道,介导细胞外核苷酸细胞间信号传导。
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