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Mouse Anti-RAB18/Cy3 Conjugated antibody (bsm-51333M-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bsm-51333M-Cy3
英文名称 Anti-RAB18/Cy3
中文名称 Cy3标记的小鼠抗G蛋白家族RAB18蛋白单克隆抗体
别    名 RAB18; RAB18 member RAS oncogene family; RAB18 small GTPase; RAB18_HUMAN; RAB18LI1; Ras-related protein Rab-18.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  转录调节因子  G蛋白信号  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 3A8
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 Recombinant human RAB18 protein
亚    型 IgG1
纯化方法 affinity purified by Protein G
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

Database links:

Entrez Gene: 22931 Human

Entrez Gene: 19330 Mouse

Entrez Gene: 307039 Rat

Omim: 602207 Human

SwissProt: Q9NP72 Human

SwissProt: P35293 Mouse

SwissProt: Q5EB77 Rat

Unigene: 406799 Human

Unigene: 132802 Mouse

Unigene: 472772 Mouse

Unigene: 53248 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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