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Rabbit Anti-Adenylate kinase isoenzyme 6/BF647 Conjugated antibody (bs-23420R-BF647)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-23420R-BF647
英文名称 Rabbit Anti-Adenylate kinase isoenzyme 6/BF647 Conjugated antibody
中文名称 BF647标记的腺苷酸激酶同工酶6抗体
别    名 AK6; Coilin Interacting Nuclear ATPase Protein; Adrenal Gland Protein AD-004; EC 2.7.4.3; HCINAP; CINAP; Coilin-Interacting Nuclear ATPase Protein; Dual Activity Adenylate Kinase/ATPase; ATP-AMP Transphosphorylase 6; Adenylate Kinase Isoenzyme 6; Coilin Interacting Protein; AK/ATPase; CGI-137; AD-004; CIP; KAD6_HUMAN;   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Adenylate kinase isoenzyme 6
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Function:
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. IMP is phosphorylated to a much lesser extent. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.

Subunit:
Monomer and homodimer (By similarity). Interacts with COIL (via C-terminus).

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system.

Similarity:
Belongs to the adenylate kinase family. AK6 subfamily.

Database links:

Entrez Gene: 102157402 Human

Entrez Gene: 6880 Human

Entrez Gene: 102216272 Mouse

Entrez Gene: 102238592 Rat

SwissProt: Q9Y3D8 Human

SwissProt: Q8VCP8 Mouse

SwissProt: Q9TTU2 Rabbit

SwissProt: Q5EB68 Rat

Unigene: 653163 Human




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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