扫码关注公众号           扫码咨询技术支持           扫码咨询技术服务
  
客服热线:400-901-9800  客服QQ:4009019800  技术答疑  技术支持  质量反馈  人才招聘  关于我们  联系我们
产品中心-北京博奥森生物技术有限公司
首页 > 产品中心 > 标记一抗 > 产品信息
Mouse Anti-human CD8/FITC Conjugated antibody (bsm-30094M-FITC) ~~~促销,代码KX240301~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
技术支持:techsupport@bioss.com.cn
说 明 书: 25T  50T  100T
25T/320.00元
50T/520.00元
100T/880.00元
大包装/询价

产品编号 bsm-30094M-FITC
英文名称 Anti-human CD8/FITC
中文名称 FITC标记的小鼠抗人CD8单克隆抗体
别    名 CD8 antigen, alpha polypeptide (p32); CD8a; CD8a antigen; CD8a molecule; CD8A_MOUSE; CD8A_HUMAN; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T cell antigen; p32; T cell antigen Leu2; T cell co receptor; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T cell antigen.  
规格价格 25T/320元 购买    50T/520元 购买    100T/880元 购买    大包装/询价
说 明 书 25T  50T  100T
研究领域 细胞生物  免疫学  细胞表面分子  t-淋巴细胞  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 HIT8a
交叉反应 Human, 
产品应用 Flow-Cyt=10ul/Test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
免 疫 原 Recombinant human CD8
亚    型 Mouse IgG1, k
纯化方法 affinity purified by Protein G
储 存 液 0.01M PBS, 0.5%BSA, 0.03% Proclin300
保存条件 Store at 2-8℃. Protect from light. Avoid freezing.
产品介绍 background:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]

Function:
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.

Subunit:
In general heterodimer of an alpha and a beta chain linked by two disulfide bonds. Can also form homodimers.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver.

Similarity:
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 925 Human

Entrez Gene: 12525 Mouse

SwissProt: P01732 Human

SwissProt: P01731 Mouse




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片
scatter diagram showing peripheral blood lymphocytes stained with bsm-30094M-FITC. The cells were incubated with the antibody (bsm-30094M-FITC, 5 µl/Test) for 30 min at 22°C. Acquisition of >10,000 events was performed.
版权所有 2004-2026 www.bioss.com.cn 北京博奥森生物技术有限公司
通过国际质量管理体系ISO 9001:2015 GB/T 19001-2016    认证编号: 00122Q31509R1M/1100
京ICP备05066980号-1         京公网安备110107000727号