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Mouse Anti-GABARAP/PE-Cy5.5 Conjugated antibody (bsm-51134M-PE-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bsm-51134M-PE-Cy5.5
英文名称1 Mouse Anti-GABARAP/PE-Cy5.5 Conjugated antibody
中文名称 PE-Cy5.5标记的小鼠抗γ-氨基丁酸受体相关蛋白单克隆抗体
别    名 ATG8A; FLC 3B; FLC3B; FLJ25768; GABA(A) receptor associated protein; GABA(A) receptor-associated protein; GABARAP a; GABARAP; Gamma aminobutyric acid receptor associated protein; Gamma-aminobutyric acid receptor-associated protein; GBRAP_HUMAN; MGC120154; MGC120155; MM 46; MM46.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  通道蛋白  细胞膜受体  G蛋白信号  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 10B2
交叉反应 (predicted: Human, Mouse, Rat, Cow, Rabbit, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 Recombinant human GABARAP protein
亚    型 IgG1
纯化方法 affinity purified by Protein G
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008]

Function:
May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.

Subunit:
Interacts with GPHN and NSF. Interacts with GABRG2, beta-tubulin and ULK1. Interacts with CALR. Interacts with DDX47. Interacts with TP53INP1 and TP53INP2. Interacts with TBC1D25.

Subcellular Location:
Endomembrane system. Cytoplasm, cytoskeleton. Golgi apparatus membrane. Largely associated with intracellular membrane structures including the Golgi apparatus and post-synaptic cisternae. Colocalizes with microtubules.

Tissue Specificity:
Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the MAP1 LC3 family.

Database links:

Entrez Gene: 11337 Human

Entrez Gene: 56486 Mouse

Entrez Gene: 58974 Rat

Omim: 605125 Human

SwissProt: O95166 Human

SwissProt: Q9DCD6 Mouse

SwissProt: P60517 Rat

Unigene: 647421 Human

Unigene: 272460 Mouse

Unigene: 8411 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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