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Rabbit
Anti-ENTPD8/Cy5.5
Cat. Number:
bs-14604R-Cy5.5
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Members of the ecto-nucleoside triphosphate diphosphohydrolase (eNTPDase) protein family are glycosylated enzymes that hydrolyze nucleoside 5’-triphosphates and 5’-diphosphates in extracellcular space. The enzymatic activities of eNTPDase are dependent on cations such as magnesium and calcium. Members of this protein family differ in their affinities for triphosphates versus diphosphates as substrate material. NTPDase8, also known as ENTPD8 (ectonucleoside triphosphate diphosphohydrolase 8) or E-NTPDase 8, is a 495 amino acid multi-pass membrane protein belonging to the GDA1/CD39 NTPase family. As a canalicular ectonucleoside NTPDase, NTPDase8 is involved in hepatic NTPDase activity and helps concentrate extracellular nucleotides. NTPDase8 binds calcium as a cofactor, becomes glycosylated following translation and exists as two alternatively spliced isoforms.
Also known as:
E NTPDase 8; ENTP8_HUMAN;
EC 3.6.1.5;
ecto-ATP-diphosphohydrolase;
Ectonucleoside triphosphate diphosphohydrolase 8;
GLSR2492;
iver ecto ATP diphosphohydrolase;
NTPDase 8;
nucleoside triphosphate diphosphohydrolase-8;
UNQ2492.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human ENTPD8.
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Predicted Molecular Weight: 54kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 675nm
Emission spectrum: 694nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.