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Cat. Number:

bs-16105R-Gold

Quantity size:

100ul   35nm

Concentration:

0.4mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC30A (tetratricopeptide repeat domain 30A) and TTC30B (tetratricopeptide repeat domain 30B) are cell projection proteins that belong to the TTC30/dfy-1/fleer family. TTC30A and TTC30B contain eight TPR repeats and may be required for polyglutamylation of axonemal tubulin. Both TTC30A and TTC30B may be involved in anterograde intraflagellar transport (IFT), which is a process where cilia precursors are transported from the base of the cilium to the site of incorporation at the tip. TTC30A and TTC30B consists of 665 amino acids and are encoded by a gene located on human chromosome 2q31.2.

Also known as:

FLJ13946; TT30A_HUMAN; Tetratricopeptide repeat domain 30A; TPR repeat protein 30A; TT30A; TTC30A.

Specificity:

Storage:

0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.

Application:

Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.