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Rabbit
Anti-Germinal Center Kinase/PE-Cy5.5
Cat. Number:
bs-16240R-PE-Cy5.5
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. [provided by RefSeq, Jul 2008]
Also known as:
GC kinase;
B lymphocyte serine/threonine protein kinase;
B lymphocyte serine/threonine-protein kinase;
BL44;
GC kinase;
GCK;
Germinal center kinase;
germinal centre kinase (GC kinase);
M4K2_HUMAN;
MAP4K2;
MAPK/ERK kinase kinase kinase 2;
MEK kinase kinase 2;
MEKKK 2;
Mitogen activated protein kinase kinase kinase kinase 2;
Mitogen-activated protein kinase kinase kinase kinase 2;
Rab8 interacting protein;
Rab8 interacting protein, formerly;
Rab8-interacting protein;
RAB8IP;
RAB8IP, formerly.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human Germinal Center Kinase.
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Predicted Molecular Weight: 91kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 496,564nm,675nm
Emission spectrum: 578nm,695nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.