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Rabbit
Anti-MYH7B/PE-Cy3
Cat. Number:
bs-9862R-PE-Cy3
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Myosin heavy chains are ubiquitous Actin-based motor proteins that convert the chemical energy derived from ATP hydrolysis into the mechanical energy that drives diverse motile processes in eukaryotic cells, including cytokinesis, vesicular transport and cellular locomotion. Muscle myosin is a heterohexamer consisting of two myosin heavy chains and two associated nonidentical pairs of myosin light chains. The seven myosin heavy chain isoforms that predominate in mammalian skeletal muscles include two developmental isoforms, MHC-embryonic (MYH3) and MHC-perinatal (MYH8); three adult skeletal muscle isoforms, MHC IIa (MYH2), MHC IIb (MYH4) and MHC IIx/d (MYH1); and MHC-∫/slow (MYH7 or MHC-∫), which is also expressed in cardiac muscle. Research indicates that mutations of the MYH7 gene causes hypertrophic cardiomyopathy.
Also known as:
adult 1;
Beta myosin heavy chain;
cardiac muscle beta isoform;
CMD1S;
CMH1;
MPD1;
MYH1;
MYH1_HUMAN;
MYH7;
MYH7_HUMAN;
Myhc slow;
MyHC-2x;
MyHC-beta;
MyHC-IIx/d;
MyHC-slow;
MYHCB;
Myopathy, distal 1;
Myosin heavy chain (AA 1-96);
Myosin heavy chain 1;
Myosin heavy chain 2x;
Myosin heavy chain 7;
Myosin heavy chain;
Myosin heavy chain IIx/d;
Myosin heavy chain slow isoform;
Myosin heavy chain, cardiac muscle beta isoform;
Myosin, heavy chain 7, cardiac muscle, beta;
Myosin, heavy polypeptide 7, cardiac muscle, beta;
Myosin-1;
Myosin-7;
Rhabdomyosarcoma antigen MU RMS 40.7A;
skeletal muscle;
SPMD.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human MYH7.
●
Predicted Molecular Weight: 213kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 488nm,532nm,561nm
Emission spectrum: 578nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.