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Rabbit
Anti-MTHFD2/Cy7
Cat. Number:
bs-17877R-Cy7
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]
Also known as:
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial;
Descriptions;
methenyltetrahydrofolate cyclohydrolase;
methylene tetrahydrofolate dehydrogenase (NAD+ dependent);
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2;
methylenetetrahydrofolate dehydrogenase (NADP+ dependent);
methylenetetrahydrofolate dehydrogenase 2;
MGC82516;
MTDC_HUMAN;
MTHFD2;
mthfd2 methylene tetrahydrofolate dehydrogenase (NAD+ dependent);
NAD-dependent methylene tetrahydrofolate dehydrogenase;
NAD-dependent methylenetetrahydrofolate dehydrogenase;
NMDMC.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human MTHFD2.
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Predicted Molecular Weight: 36kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 710nm,743nm
Emission spectrum: 767nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.