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Rabbit
Anti-phospho-PDGFRA (Tyr720)/BF594
Cat. Number:
bs-12595R-BF594
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Also known as:
PDGF Receptor alpha (phospho Y720); p-PDGF Receptor alpha (phospho Y720);
Alpha-type platelet-derived growth factor receptor;
CD140 antigen-like family member A;
CD140a;
CD140a antigen;
MGC74795;
PDGF alpha chain;
PDGF-R-alpha;
PDGFR 2;
PDGFR alpha;
PDGFR2;
PDGFRA;
PDGFRA/BCR fusion;
PGFRA_HUMAN;
Platelet derived growth factor receptor 2;
Platelet derived growth factor receptor alpha;
Platelet derived growth factor receptor alpha polypeptide;
Platelet derived growth factor receptor;
Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein;
RHEPDGFRA.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthesised phosphopeptide derived from human PDGFRA around the phosphorylation site of Tyr720.
●
Predicted Molecular Weight: 123kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.